ICDcodes.org
FY2027

E52 vs E64.8

E52 and E64.8 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.

The official note, declared on E52
sequelae of niacin deficiency (E64.8)
E52

Niacin deficiency [pellagra]

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E50-E64
Use when the record says
  • Niacin (-tryptophan) deficiency
  • Nicotinamide deficiency
  • Pellagra (alcoholic)
Indexed under
  • Niacindeficiency (amide)
  • Nicotinic acid deficiency
  • Pellagra (alcoholic)
  • Alcohol, alcoholic, alcohol-induced › pellagra
  • Avitaminosis › nicotinic acid (multiple)
E64.8

Sequelae of other nutritional deficiencies

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E50-E64
Indexed under
  • Sequelae › calcium deficiency (of)
  • Sequelae › niacin deficiency (of)
  • Sequelae › selenium deficiency (of)
  • Sequelae › thiamine deficiency (of)
  • Sequelae › vitamin deficiency NEC (of)

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027