Excludes1 pair

E34.8 vs E79-

E34.8 and E79 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on E79
progeria (E34.8)
E34.8

Other specified endocrine disorders

BillableUnspecified
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E20-E35
Use when the record says
  • Pineal gland dysfunction
  • Progeria
Indexed under
  • Donohue's syndrome
  • Gilford-Hutchinson disease
  • Hutchinson-Gilford disease or syndrome
  • Hyperpinealism
  • Hypopinealism
E79

Disorders of purine and pyrimidine metabolism

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027