E27.1 vs E85
E27.1 and E85 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E27.1
amyloidosis (E85.-)
E27.1
Primary adrenocortical insufficiency
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Addison's disease
- Autoimmune adrenalitis
Indexed under
- Addison's › diseaseor syndrome
- Adrenalitis, adrenitis › autoimmune
- Disease, diseased › bronze Addison's
- Hypoadrenalism, hypoadrenia › primary
- Hypoadrenocorticism › primary
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027