E25 vs E30.1
E25 and E30.1 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E30.1
female heterosexual precocious pseudopuberty (E25.-)
E25
Adrenogenital disorders
Not billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
- Female adrenal pseudohermaphroditism
- Female heterosexual precocious pseudopuberty
- Male isosexual precocious pseudopuberty
- Male macrogenitosomia praecox
- Male sexual precocity with adrenal hyperplasia
- Male virilization (female)
E30.1
Precocious puberty
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Precocious menstruation
Indexed under
- Precocity, sexual (constitutional) (cryptogenic) (female) (idiopathic) (male)
- Pubarche, precocious
- Pubertas praecox
- Breast › buds
- Buds › breast
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027