FY2027
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Excludes1 pair

E25- vs E30.1

E25 and E30.1 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on E30.1
female heterosexual precocious pseudopuberty (E25.-)
E25

Adrenogenital disorders

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E20-E35
Use when the record says
  • adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
  • Female adrenal pseudohermaphroditism
  • Female heterosexual precocious pseudopuberty
  • Male isosexual precocious pseudopuberty
  • Male macrogenitosomia praecox
  • Male sexual precocity with adrenal hyperplasia
  • Male virilization (female)
E30.1

Precocious puberty

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E20-E35
Use when the record says
  • Precocious menstruation
Indexed under
  • Precocity, sexual (constitutional) (cryptogenic) (female) (idiopathic) (male)
  • Pubarche, precocious
  • Pubertas praecox
  • Breast › buds
  • Buds › breast

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027