E25.0 vs E30.1
E25.0 and E30.1 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E30.1
congenital adrenal hyperplasia (E25.0)
E25.0
Congenital adrenogenital disorders associated with enzyme deficiency
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Congenital adrenal hyperplasia
- 21-Hydroxylase deficiency
- Salt-losing congenital adrenal hyperplasia
Indexed under
- Adrenogenitalism, congenital
- Adrenogenital syndrome › congenital
- Adrenogenital syndrome › salt loss
- Defect, defective › 3-beta-hydroxysteroid dehydrogenase
- Defect, defective › 11-hydroxylase
E30.1
Precocious puberty
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Precocious menstruation
Indexed under
- Precocity, sexual (constitutional) (cryptogenic) (female) (idiopathic) (male)
- Pubarche, precocious
- Pubertas praecox
- Breast › buds
- Buds › breast
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027