Excludes1 pair

E24- vs E27.0

E24 and E27.0 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on E27.0
Cushing's syndrome (E24.-)
E24

Cushing's syndrome

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E20-E35
E27.0

Other adrenocortical overactivity

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E20-E35
Use when the record says
  • Overproduction of ACTH, not associated with Cushing's disease
  • Premature adrenarche
Indexed under
  • Adrenarche, premature
  • Schroeder's syndrome (endocrine hypertensive)
  • Slocumb's syndrome
  • Dysadrenocortism › hyperfunction
  • Hyperadrenocorticism › not associated with Cushing's syndrome

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027