E24 vs E27.0
E24 and E27.0 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E27.0
Cushing's syndrome (E24.-)
E24
Cushing's syndrome
Not billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
E27.0
Other adrenocortical overactivity
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Overproduction of ACTH, not associated with Cushing's disease
- Premature adrenarche
Indexed under
- Adrenarche, premature
- Schroeder's syndrome (endocrine hypertensive)
- Slocumb's syndrome
- Dysadrenocortism › hyperfunction
- Hyperadrenocorticism › not associated with Cushing's syndrome
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027