E24.3 vs E34.2
E24.3 and E34.2 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E34.2
ectopic ACTH syndrome (E24.3)
E24.3
Ectopic ACTH syndrome
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Indexed under
- ACTH ectopic syndrome
- Ectopic, ectopia › ACTH syndrome (congenital)
- Syndrome › ectopic ACTH
- Syndrome › Cushing's › due to › ectopic ACTH
E34.2
Ectopic hormone secretion, not elsewhere classified
BillableUnspecified
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Indexed under
- Ectopic, ectopia › hormone secretion NEC (congenital)
- Secretion › hormone › ectopic NEC
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027