E23.0 vs E28
E23.0 and E28 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E28
isolated gonadotropin deficiency (E23.0)
E23.0
Hypopituitarism
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Fertile eunuch syndrome
- Hypogonadotropic hypogonadism
- Idiopathic growth hormone deficiency
- Isolated deficiency of gonadotropin
- Isolated deficiency of growth hormone
- Isolated deficiency of pituitary hormone
- Kallmann's syndrome
- Lorain-Levi short stature
Indexed under
- Ahumada-del Castillo syndrome
- Fertile eunuch syndrome
- Hypopituitarism (juvenile)
- Kallmann's syndrome
- Lorainshort stature syndrome (-Levi)
E28
Ovarian dysfunction
Not billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027