E22.8 vs E30.1
E22.8 and E30.1 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E30.1
central precocious puberty (E22.8)
E22.8
Other hyperfunction of pituitary gland
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Central precocious puberty
Indexed under
- Hyperfunction › pituitary › specified NEC
- Precocious › puberty › central
- Puberty › precocious › central (development state)
- Puberty › premature › due to › pituitaryhyperfunction (development state)
E30.1
Precocious puberty
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Use when the record says
- Precocious menstruation
Indexed under
- Precocity, sexual (constitutional) (cryptogenic) (female) (idiopathic) (male)
- Pubarche, precocious
- Pubertas praecox
- Breast › buds
- Buds › breast
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027