E22.2 vs E87.1
E22.2 and E87.1 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on E87.1
syndrome of inappropriate secretion of antidiuretic hormone (E22.2)
E22.2
Syndrome of inappropriate secretion of antidiuretic hormone
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E20-E35
Indexed under
- Antidiuretic hormone syndrome
- Schwartz-Bartter syndrome
- Secretion › antidiuretic hormone, inappropriate
- Syndrome › inappropriate secretion of antidiuretic hormone
- Syndrome › Schwartz-Bartter
E87.1
Hypo-osmolality and hyponatremia
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E70-E88
Use when the record says
- Sodium [Na] deficiency
Indexed under
- Hyponatremia
- Hypo-osmolality
- Cramp › salt-depletion (s)
- Deficiency, deficient › natrium
- Deficiency, deficient › salt
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027