Excludes1 pair
E16.3 vs E74-
E16.3 and E74 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.
The official note, declared on E74
increased secretion of glucagon (E16.3)
E16.3
Increased secretion of glucagon
Billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E15-E16
Use when the record says
- Hyperplasia of pancreatic endocrine cells with glucagon excess
Indexed under
- Abnormal, abnormality, abnormalities › glucagon secretion
- Excess, excessive, excessively › glucagon
- Hypersecretion › glucagon
- Abnormal, abnormality, abnormalities › secretion › glucagon
- Increase, increased › secretion › glucagon
E74
Other disorders of carbohydrate metabolism
Not billable
- Chapter 4
- Endocrine, nutritional and metabolic diseases
- Section
- E70-E88
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027