Excludes1 pair

D66 vs D68.0-

D66 and D68.0 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D68.0
factor VIII deficiency NOS (D66)
D66

Hereditary factor VIII deficiency

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D65-D69
Use when the record says
  • Classical hemophilia
  • Deficiency factor VIII (with functional defect)
  • Hemophilia NOS
  • Hemophilia A
Indexed under
  • Hemophilia (classical) (familial) (hereditary)
  • Subhemophilia
  • Arthropathy › hemophilic NEC
  • Disease, diseased › bleeder's
  • Hemophilia › A
D68.0

Von Willebrand disease

Not billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D65-D69

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027