Excludes1 pair

D66 vs D68-

D66 and D68 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D66
factor VIII deficiency with vascular defect (D68.0-)
D66

Hereditary factor VIII deficiency

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D65-D69
Use when the record says
  • Classical hemophilia
  • Deficiency factor VIII (with functional defect)
  • Hemophilia NOS
  • Hemophilia A
Indexed under
  • Hemophilia (classical) (familial) (hereditary)
  • Subhemophilia
  • Arthropathy › hemophilic NEC
  • Disease, diseased › bleeder's
  • Hemophilia › A
D68

Other coagulation defects

Not billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D65-D69

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027