Excludes1 pair

D61.1 vs D63.0

D61.1 and D63.0 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D63.0
aplastic anemia due to antineoplastic chemotherapy (D61.1)
D61.1

Drug-induced aplastic anemia

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D60-D64
Indexed under
  • Anemia › aplastic › drug-induced
  • Anemia › aplastic › due to › drugs
D63.0

Anemia in neoplastic disease

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D60-D64
Indexed under
  • Anemia › in › neoplastic disease

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027