D61.1 vs D63.0
D61.1 and D63.0 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on D63.0
aplastic anemia due to antineoplastic chemotherapy (D61.1)
D61.1
Drug-induced aplastic anemia
Billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D60-D64
Indexed under
- Anemia › aplastic › drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- Anemia › aplastic › due to › drugs (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
D63.0
Anemia in neoplastic disease
Billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D60-D64
Indexed under
- Anemia › in › neoplastic disease (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027