FY2027
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Excludes1 pair

D59- vs N08

D59 and N08 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on N08
hemolytic-uremic syndrome (D59.3-)
D59

Acquired hemolytic anemia

Not billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D55-D59
N08

Glomerular disorders in diseases classified elsewhere

Billable
Chapter 14
Diseases of the genitourinary system
Section
N00-N08
Use when the record says
  • Glomerulonephritis
  • Nephritis
  • Nephropathy
Indexed under
  • Nephritis, nephritic › amyloid
  • Nephropathy › sickle-cell
  • Disorder › glomerular › amyloidosis
  • Disorder › glomerular › cryoglobulinemia
  • Disorder › glomerular › disseminated intravascular coagulation

These two codes sit in different chapters of the Tabular List, which is usually the clearest signal that they describe different underlying processes rather than different degrees of the same one.

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027