Excludes1 pair

D55.0 vs D75.A

D55.0 and D75.A are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D55.0
glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia (D75.A)
D55.0

Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D55-D59
Use when the record says
  • Favism
  • G6PD deficiency anemia
Indexed under
  • Favism (anemia)
  • Anemia › Baghdad spring
  • Anemia › favism
  • Anemia › glucose-6-phosphate dehydrogenase deficiency (G6PD)
  • Poisoning › fava bean
D75.A

Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

Billable
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Section
D70-D77
Indexed under
  • Deficiency, deficient › glucose-6-phosphate dehydrogenase › without anemia

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027