Excludes1 pair

D21- vs D28.2

D21 and D28.2 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D21
benign neoplasm of uterine ligament, any (D28.2)
D21

Other benign neoplasms of connective and other soft tissue

Not billable
Chapter 2
Neoplasms
Section
D10-D36
Use when the record says
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat
  • benign neoplasm of ligament, except uterine
  • benign neoplasm of lymphatic channel
  • benign neoplasm of muscle
D28.2

Benign neoplasm of uterine tubes and ligaments

Billable
Chapter 2
Neoplasms
Section
D10-D36
Use when the record says
  • Benign neoplasm of fallopian tube
  • Benign neoplasm of uterine ligament (broad) (round)
Indexed under
  • Endosalpingioma

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027