Excludes1 pair

C93- vs D46.Z

C93 and D46.Z are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on D46.Z
chronic myelomonocytic leukemia (C93.1-)
C93

Monocytic leukemia

Not billable
Chapter 2
Neoplasms
Section
C81-C96
Use when the record says
  • monocytoid leukemia
D46.Z

Other myelodysplastic syndromes

Billable
Chapter 2
Neoplasms
Section
D37-D48
Indexed under
  • Myelodysplasia › specified NEC
  • Myelodysplastic syndrome › specified NEC
  • Syndrome › myelodysplastic › specified NEC

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027