Excludes1 pair

C83.3- vs C85-

C83.3 and C85 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on C83.3
mediastinal (thymic) large B-cell lymphoma (C85.2-)
C83.3

Diffuse large B-cell lymphoma

Not billable
Chapter 2
Neoplasms
Section
C81-C96
Use when the record says
  • Anaplastic diffuse large B-cell lymphoma
  • CD30-positive diffuse large B-cell lymphoma
  • Centroblastic diffuse large B-cell lymphoma
  • Diffuse large B-cell lymphoma, subtype not specified
  • Immunoblastic diffuse large B-cell lymphoma
  • Plasmablastic diffuse large B-cell lymphoma
  • T-cell rich diffuse large B-cell lymphoma
Indexed under
  • Lymphoma › diffuse large cell
  • Lymphoma › diffuse large cell › anaplastic
  • Lymphoma › diffuse large cell › B-cell
  • Lymphoma › diffuse large cell › CD30-positive
  • Lymphoma › diffuse large cell › centroblastic
C85

Other specified and unspecified types of non-Hodgkin lymphoma

Not billable
Chapter 2
Neoplasms
Section
C81-C96

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027