C79.9 vs C80.1
C79.9 and C80.1 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter. The distinction is primary vs secondary.
The official note, declared on C79.9
malignant (primary) neoplasm of unspecified site (C80.1)
C79.9
Secondary malignant neoplasm of unspecified site
BillableUnspecified
- Chapter 2
- Neoplasms
- Section
- C76-C80
Use when the record says
- Metastatic cancer NOS
- Metastatic disease NOS
Indexed under
- Disease, diseased › metastatic
- Metastasis, metastatic › disease
C80.1
Malignant (primary) neoplasm, unspecified
BillableUnspecified
- Chapter 2
- Neoplasms
- Section
- C76-C80
Use when the record says
- Cancer NOS
- Cancer unspecified site (primary)
- Carcinoma unspecified site (primary)
- Malignancy unspecified site (primary)
Indexed under
- Cancer › unspecified site
- Carcinoma › unspecified site (malignant)
- Malignancy › unspecified site
- Sarcomatosis › unspecified site
- Tumor › malignant
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027