ICDcodes.org
FY2027

C64 vs C65

C64 and C65 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.

The official note, declared on C64
malignant neoplasm of renal calyces (C65.-)
C64

Malignant neoplasm of kidney, except renal pelvis

Not billable
Chapter 2
Neoplasms
Section
C64-C68
Indexed under
  • Nephroblastoma (epithelial) (mesenchymal)
  • Nephroma
  • Wilms' tumor
  • Adenocarcinoma › renal cell
  • Carcinoma › renal cell (malignant)
C65

Malignant neoplasm of renal pelvis

Not billable
Chapter 2
Neoplasms
Section
C64-C68
Use when the record says
  • malignant neoplasm of pelviureteric junction
  • malignant neoplasm of renal calyces

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027