Excludes1 pair

C37 vs C49.3

C37 and C49.3 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on C49.3
malignant neoplasm of thymus (C37)
C37

Malignant neoplasm of thymus

Billable
Chapter 2
Neoplasms
Section
C30-C39
Indexed under
  • Carcinoma › thymic
  • Thymoma › malignant
  • Thymoma › metaplastic
  • Thymoma › sclerosing
  • Thymoma › type A
C49.3

Malignant neoplasm of connective and soft tissue of thorax

Billable
Chapter 2
Neoplasms
Section
C45-C49
Use when the record says
  • Malignant neoplasm of axilla
  • Malignant neoplasm of diaphragm
  • Malignant neoplasm of great vessels

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027