ICDcodes.org
FY2027

Z79.81Long term (current) use of agents affecting estrogen receptors and estrogen levels

Not billable

Is Z79.81 billable?

No — Z79.81 is a non-billable header code. Z79.81 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 3 billable codes beneath Z79.81.

Z79.81 at a glance

CodeZ79.81
DescriptionLong term (current) use of agents affecting estrogen receptors and estrogen levels
BillableNo — header code
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Excludes1 — never code together

The conditions below can never be reported together with Z79.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • hormone replacement therapy (Z79.890)

Code first

The underlying condition below must be sequenced before Z79.81. Z79.81 describes a manifestation and cannot be the principal or first-listed diagnosis.

  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)

Use additional code

Report an additional code alongside Z79.81 to fully describe the condition. Z79.81 is sequenced first.

  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)

Excludes2 — not included here — inherited from Z79

The conditions below are not part of Z79.81, but a patient may have both at the same time. When documentation supports it, Z79.81 and the excluded code may both be reported.

  • drug abuse and dependence (F11-F19)
  • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)

Code also — inherited from Z77-Z99

Two codes may be needed to describe the condition fully. Whether Z79.81 is sequenced first depends on the reason for the encounter.

  • any follow-up examination (Z08-Z09)

Code also — inherited from Z79

Two codes may be needed to describe the condition fully. Whether Z79.81 is sequenced first depends on the reason for the encounter.

  • any therapeutic drug level monitoring (Z51.81)

What codes fall under Z79.81? (3)

How long has Z79.81 existed?

Z79.81 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the Z79.8 family? (5)