ICDcodes.org
FY2027

T80.22XS — Acute infection following transfusion, infusion, or injection of blood and blood products, sequela

Billable

Is T80.22XS billable?

Yes — T80.22XS is billable for FY2027. T80.22XS is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. T80.22XS may be submitted for encounters from October 1, 2026 through September 30, 2027.

T80.22XS at a glance

CodeT80.22XS
DescriptionAcute infection following transfusion, infusion, or injection of blood and blood products, sequela
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027
7th character "S"sequela

What does the 7th character "S" mean in T80.22XS?

In T80.22XS, the 7th character S means sequela. The 7th character is required for T80.22XS to be a valid, complete code.

Same condition, different episode of care — switch the 7th character:

Which MS-DRGs does T80.22XS group to?

T80.22XS sits in MDC 21 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 922Other Injury, Poisoning and Toxic Effect Diagnoses with MCCmedical
  • 923Other Injury, Poisoning and Toxic Effect Diagnoses without MCCmedical

How is T80.22XS listed in the Alphabetic Index?

The Alphabetic Index lists these routes under T80.22, the nearest indexed parent of T80.22XS. Use them to find the family, then select the specific code.

  • Complication › transfusion › infection › acute (s) (from) (of)
  • Infection, infected, infective › due to or resulting from › infusion, injection or transfusion NEC › acute (opportunistic)

Use additional code — inherited from Chapter 19

Report an additional code alongside T80.22XS to fully describe the condition. T80.22XS is sequenced first.

  • code to identify any retained foreign body, if applicable (Z18.-)

Use additional code — inherited from T80-T88

Report an additional code alongside T80.22XS to fully describe the condition. T80.22XS is sequenced first.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code(s) to identify the specified condition resulting from the complication
  • code to identify devices involved and details of circumstances (Y62-Y82)

Use additional code — inherited from T80.2

Report an additional code alongside T80.22XS to fully describe the condition. T80.22XS is sequenced first.

  • code to identify the specific infection, such as:
  • sepsis (A41.9)
  • code (R65.2-) to identify severe sepsis, if applicable

Excludes2 — not included here — inherited from Chapter 19

The conditions below are not part of T80.22XS, but a patient may have both at the same time. When documentation supports it, T80.22XS and the excluded code may both be reported.

  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Excludes2 — not included here — inherited from T80-T88

The conditions below are not part of T80.22XS, but a patient may have both at the same time. When documentation supports it, T80.22XS and the excluded code may both be reported.

  • any encounters with medical care for postprocedural conditions in which no complications are present, such as:
  • artificial opening status (Z93.-)
  • closure of external stoma (Z43.-)
  • fitting and adjustment of external prosthetic device (Z44.-)
  • burns and corrosions from local applications and irradiation (T20-T32)
  • complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
  • mechanical complication of respirator [ventilator] (J95.850)
  • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
  • postprocedural fever (R50.82)
  • specified complications classified elsewhere, such as:
  • cerebrospinal fluid leak from spinal puncture (G97.0)
  • colostomy malfunction (K94.0-)
  • disorders of fluid and electrolyte imbalance (E86-E87)
  • functional disturbances following cardiac surgery (I97.0-I97.1)
  • intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
  • ostomy complications (J95.0-, K94.-, N99.5-)
  • postgastric surgery syndromes (K91.1)
  • postlaminectomy syndrome NEC (M96.1)
  • postmastectomy lymphedema syndrome (I97.2)
  • postsurgical blind-loop syndrome (K91.2)
  • ventilator associated pneumonia (J95.851)

Excludes2 — not included here — inherited from T80

The conditions below are not part of T80.22XS, but a patient may have both at the same time. When documentation supports it, T80.22XS and the excluded code may both be reported.

  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)

Excludes2 — not included here — inherited from T80.2

The conditions below are not part of T80.22XS, but a patient may have both at the same time. When documentation supports it, T80.22XS and the excluded code may both be reported.

  • infections specified as due to prosthetic devices, implants and grafts (T82.6-T82.7, T83.5-T83.6, T84.5-T84.7, T85.7)
  • postprocedural infections (T81.4-)

How long has T80.22XS existed?

T80.22XS has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.