ICDcodes.org
FY2027

T45.AX4DPoisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined, subsequent encounter

Billable

Is T45.AX4D billable?

Yes — T45.AX4D is billable for FY2027. T45.AX4D is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. T45.AX4D may be submitted for encounters from October 1, 2026 through September 30, 2027.

T45.AX4D at a glance

CodeT45.AX4D
DescriptionPoisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined, subsequent encounter
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027
7th character "D"subsequent encounter

What does the 7th character "D" mean in T45.AX4D?

In T45.AX4D, the 7th character D means subsequent encounter. The 7th character is required for T45.AX4D to be a valid, complete code.

Same condition, different episode of care — switch the 7th character:

Which MS-DRGs does T45.AX4D group to?

T45.AX4D sits in MDC 23 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 949Aftercare with CC/MCCmedical
  • 950Aftercare without CC/MCCmedical

Excludes1 — never code together — inherited from T36-T50

The conditions below can never be reported together with T45.AX4D on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes1 — never code together — inherited from T45.A

The conditions below can never be reported together with T45.AX4D on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drug (T45.1)

Code first — inherited from T36-T50

The underlying condition below must be sequenced before T45.AX4D. T45.AX4D describes a manifestation and cannot be the principal or first-listed diagnosis.

  • , for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use additional code — inherited from Chapter 19

Report an additional code alongside T45.AX4D to fully describe the condition. T45.AX4D is sequenced first.

  • code to identify any retained foreign body, if applicable (Z18.-)

Use additional code — inherited from T36-T50

Report an additional code alongside T45.AX4D to fully describe the condition. T45.AX4D is sequenced first.

  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)

Excludes2 — not included here — inherited from Chapter 19

The conditions below are not part of T45.AX4D, but a patient may have both at the same time. When documentation supports it, T45.AX4D and the excluded code may both be reported.

  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Excludes2 — not included here — inherited from T36-T50

The conditions below are not part of T45.AX4D, but a patient may have both at the same time. When documentation supports it, T45.AX4D and the excluded code may both be reported.

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)

How long has T45.AX4D existed?

T45.AX4D first appears in FY2025.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.