R74.8 — Abnormal levels of other serum enzymes
Is R74.8 billable?
Yes — R74.8 is billable for FY2027. R74.8 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. R74.8 may be submitted for encounters from October 1, 2026 through September 30, 2027.
R74.8 at a glance
| Code | R74.8 |
|---|---|
| Description | Abnormal levels of other serum enzymes |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does R74.8 group to?
R74.8 sits in MDC 23 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 947Signs and Symptoms with MCCmedical
- 948Signs and Symptoms without MCCmedical
How is R74.8 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to R74.8. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Abnormal, abnormality, abnormalities › serum level › acid phosphatase
- Abnormal, abnormality, abnormalities › serum level › alkaline phosphatase
- Abnormal, abnormality, abnormalities › serum level › amylase
- Abnormal, abnormality, abnormalities › serum level › lipase
- Abnormal, abnormality, abnormalities › serum level › triacylglycerol lipase
- Abnormal, abnormality, abnormalities › serum level › enzymes › specified NEC
- Elevated, elevation › liver function › test › alkaline phosphatase
- Elevated, elevation › liver function › test › hepatic enzyme
Inclusion terms
Alternative wording in documentation that is classified to R74.8.
- Abnormal level of acid phosphatase
- Abnormal level of alkaline phosphatase
- Abnormal level of amylase
- Abnormal level of lipase [triacylglycerol lipase]
Excludes2 — not included here — inherited from Chapter 18
The conditions below are not part of R74.8, but a patient may have both at the same time. When documentation supports it, R74.8 and the excluded code may both be reported.
Excludes2 — not included here — inherited from R70-R79
The conditions below are not part of R74.8, but a patient may have both at the same time. When documentation supports it, R74.8 and the excluded code may both be reported.
- abnormal findings on antenatal screening of mother (O28.-)
- abnormalities of lipids (E78.-)
- abnormalities of platelets and thrombocytes (D69.-)
- abnormalities of white blood cells classified elsewhere (D70-D72)
- coagulation hemorrhagic disorders (D65-D68)
- diagnostic abnormal findings classified elsewhere - see Alphabetical Index
- hemorrhagic and hematological disorders of newborn (P50-P61)
How long has R74.8 existed?
R74.8 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.