E83.821 — ENPP1 deficiency causing generalized arterial calcification of infancy
Is E83.821 billable?
Yes — E83.821 is billable for FY2027. E83.821 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E83.821 may be submitted for encounters from October 1, 2026 through September 30, 2027.
E83.821 at a glance
| Code | E83.821 |
|---|---|
| Description | ENPP1 deficiency causing generalized arterial calcification of infancy |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does E83.821 group to?
E83.821 sits in MDC 05 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 299Peripheral Vascular Disorders with MCCmedical
- 300Peripheral Vascular Disorders with CCmedical
- 301Peripheral Vascular Disorders without CC/MCCmedical
As a secondary diagnosis, E83.821 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is E83.821 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to E83.821. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Deficiency, deficient › ENPP1 › causing › generalized arterial calcification of infancy
- Calcification › arterial › generalized, of infancy › with › ENPP1 deficiency
Code also
Two codes may be needed to describe the condition fully. Whether E83.821 is sequenced first depends on the reason for the encounter.
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E83.821 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E70-E88
The conditions below can never be reported together with E83.821 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from E83
The conditions below can never be reported together with E83.821 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from E70-E88
The conditions below are not part of E83.821, but a patient may have both at the same time. When documentation supports it, E83.821 and the excluded code may both be reported.
- Ehlers-Danlos syndromes (Q79.6-)
How long has E83.821 existed?
E83.821 first appears in FY2026.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
What other codes are in the E83.82 family? (5)
- E83.820Generalized arterial calcification of infancy with unspecified genetic causality
- E83.822ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2
- E83.823ABCC6 deficiency causing generalized arterial calcification of infancy
- E83.824ABCC6 deficiency causing pseudoxanthoma elasticum
- E83.825CD73 deficiency causing arterial calcification