E53.1 — Pyridoxine deficiency
Is E53.1 billable?
Yes — E53.1 is billable for FY2027. E53.1 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E53.1 may be submitted for encounters from October 1, 2026 through September 30, 2027.
E53.1 at a glance
| Code | E53.1 |
|---|---|
| Description | Pyridoxine deficiency |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does E53.1 group to?
E53.1 sits in MDC 10 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 640Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCCmedical
- 641Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCCmedical
How is E53.1 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to E53.1. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Avitaminosis › B6 (multiple)
- Deficiency, deficient › pyracin
- Deficiency, deficient › pyridoxal
- Deficiency, deficient › pyridoxamine
- Deficiency, deficient › pyridoxine
- Dependence › vitamin B6 (on) (syndrome)
- Syndrome › vitamin B6 deficiency
- Deficiency, deficient › vitaminNOS › B6
- Polyneuropathy › in › deficiency › vitamin B6 (peripheral)
Excludes1 — never code together
The conditions below can never be reported together with E53.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- pyridoxine-responsive sideroblastic anemia (D64.3)
Inclusion terms
Alternative wording in documentation that is classified to E53.1.
- Vitamin B6 deficiency
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E53.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E53
The conditions below can never be reported together with E53.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- sequelae of vitamin B deficiency (E64.8)
Excludes2 — not included here — inherited from E50-E64
The conditions below are not part of E53.1, but a patient may have both at the same time. When documentation supports it, E53.1 and the excluded code may both be reported.
- nutritional anemias (D50-D53)
How long has E53.1 existed?
E53.1 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with E53.1?
ICD-10-CM declares these codes mutually exclusive with E53.1 — exactly one of each pair can be correct for a given encounter.