D81.7 — Major histocompatibility complex class II deficiency
Is D81.7 billable?
Yes — D81.7 is billable for FY2027. D81.7 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. D81.7 may be submitted for encounters from October 1, 2026 through September 30, 2027.
D81.7 at a glance
| Code | D81.7 |
|---|---|
| Description | Major histocompatibility complex class II deficiency |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does D81.7 group to?
D81.7 sits in MDC 16 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 808Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCCmedical
- 809Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CCmedical
- 810Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCCmedical
As a secondary diagnosis, D81.7 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is D81.7 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to D81.7. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Deficiency, deficient › major histocompatibility complex › class II
Excludes1 — never code together — inherited from D80-D89
The conditions below can never be reported together with D81.7 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from D81
The conditions below can never be reported together with D81.7 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- autosomal recessive agammaglobulinemia (Swiss type) (D80.0)
Excludes2 — not included here — inherited from Chapter 3
The conditions below are not part of D81.7, but a patient may have both at the same time. When documentation supports it, D81.7 and the excluded code may both be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Excludes2 — not included here — inherited from D80-D89
The conditions below are not part of D81.7, but a patient may have both at the same time. When documentation supports it, D81.7 and the excluded code may both be reported.
- human immunodeficiency virus [HIV] disease (B20)
How long has D81.7 existed?
D81.7 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
What other codes are in the D81 family? (9)
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3Adenosine deaminase [ADA] deficiencynot billable
- D81.4Nezelof's syndrome
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.8Other combined immunodeficienciesnot billable
- D81.9Combined immunodeficiency, unspecified