D76.2 — Hemophagocytic syndrome, infection-associated
Is D76.2 billable?
Yes — D76.2 is billable for FY2027. D76.2 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. D76.2 may be submitted for encounters from October 1, 2026 through September 30, 2027.
D76.2 at a glance
| Code | D76.2 |
|---|---|
| Description | Hemophagocytic syndrome, infection-associated |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does D76.2 group to?
D76.2 sits in MDC 16 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 814Reticuloendothelial and Immunity Disorders with MCCmedical
- 815Reticuloendothelial and Immunity Disorders with CCmedical
- 816Reticuloendothelial and Immunity Disorders without CC/MCCmedical
As a secondary diagnosis, D76.2 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is D76.2 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to D76.2. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Syndrome › hemophagocytic, infection-associated
- Syndrome › macrophage activation › due to infection
Use additional code
Report an additional code alongside D76.2 to fully describe the condition. D76.2 is sequenced first.
- code to identify infectious agent or disease.
Excludes1 — never code together — inherited from D76
The conditions below can never be reported together with D76.2 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- (Abt-) Letterer-Siwe disease (C96.0)
- eosinophilic granuloma (C96.6)
- Hand-Schüller-Christian disease (C96.5)
- histiocytic medullary reticulosis (C96.9)
- histiocytic sarcoma (C96.A)
- histiocytosis X, multifocal (C96.5)
- histiocytosis X, unifocal (C96.6)
- Langerhans-cell histiocytosis, multifocal (C96.5)
- Langerhans-cell histiocytosis NOS (C96.6)
- Langerhans-cell histiocytosis, unifocal (C96.6)
- leukemic reticuloendotheliosis (C91.4-)
- lipomelanotic reticulosis (I89.8)
- malignant histiocytosis (C96.A)
- malignant reticulosis (C86.0)
- nonlipid reticuloendotheliosis (C96.0)
Excludes2 — not included here — inherited from Chapter 3
The conditions below are not part of D76.2, but a patient may have both at the same time. When documentation supports it, D76.2 and the excluded code may both be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
How long has D76.2 existed?
D76.2 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.