C88.2 — Heavy chain disease

Not billable

Is C88.2 billable?

No — C88.2 is a non-billable header code. C88.2 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 2 billable codes beneath C88.2.

Billable codes under this header

C88.2 at a glance

Code	C88.2
Description	Heavy chain disease
Billable	No — header code
Code set	ICD-10-CM FY2027
Valid for encounters	October 1, 2026 – September 30, 2027

How is C88.2 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to C88.2. They show the wording a clinician may have documented, which often differs from the Tabular description.

Franklin disease
Disease, diseased › Franklin
Disease, diseased › gamma heavy chain
Disease, diseased › heavy chain NEC
Disease, diseased › mu heavy chain disease
Disease, diseased › heavy chain NEC › gamma
Disease, diseased › heavy chain NEC › mu

Inclusion terms

Alternative wording in documentation that is classified to C88.2.

Franklin disease
Gamma heavy chain disease
Mu heavy chain disease

Excludes1 — never code together — inherited from C88

The conditions below can never be reported together with C88.2 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

B-cell lymphoma, unspecified (C85.1-)
personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Excludes2 — not included here — inherited from C81-C96

The conditions below are not part of C88.2, but a patient may have both at the same time. When documentation supports it, C88.2 and the excluded code may both be reported.

Kaposi's sarcoma of lymph nodes (C46.3)
secondary and unspecified neoplasm of lymph nodes (C77.-)
secondary neoplasm of bone marrow (C79.52)
secondary neoplasm of spleen (C78.89)

What codes fall under C88.2? (2)

How long has C88.2 existed?

C88.2 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

FY2025: C88.2 stopped being billable

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.