T80.6 — Other serum reactions
Is T80.6 billable?
No — T80.6 is a non-billable header code. T80.6 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 9 billable codes beneath T80.6.
Billable codes under this header
- T80.61XAOther serum reaction due to administration of blood and blood products, initial encounter
- T80.61XDOther serum reaction due to administration of blood and blood products, subsequent encounter
- T80.61XSOther serum reaction due to administration of blood and blood products, sequela
- T80.62XAOther serum reaction due to vaccination, initial encounter
- T80.62XDOther serum reaction due to vaccination, subsequent encounter
- T80.62XSOther serum reaction due to vaccination, sequela
- T80.69XAOther serum reaction due to other serum, initial encounter
- T80.69XDOther serum reaction due to other serum, subsequent encounter
- T80.69XSOther serum reaction due to other serum, sequela
T80.6 at a glance
| Code | T80.6 |
|---|---|
| Description | Other serum reactions |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes2 — not included here
The conditions below are not part of T80.6, but a patient may have both at the same time. When documentation supports it, T80.6 and the excluded code may both be reported.
- serum hepatitis (B16-B19)
Inclusion terms
Alternative wording in documentation that is classified to T80.6.
- Intoxication by serum
- Protein sickness
- Serum rash
- Serum sickness
- Serum urticaria
Use additional code — inherited from Chapter 19
Report an additional code alongside T80.6 to fully describe the condition. T80.6 is sequenced first.
- code to identify any retained foreign body, if applicable (Z18.-)
Use additional code — inherited from T80-T88
Report an additional code alongside T80.6 to fully describe the condition. T80.6 is sequenced first.
Excludes2 — not included here — inherited from Chapter 19
The conditions below are not part of T80.6, but a patient may have both at the same time. When documentation supports it, T80.6 and the excluded code may both be reported.
Excludes2 — not included here — inherited from T80-T88
The conditions below are not part of T80.6, but a patient may have both at the same time. When documentation supports it, T80.6 and the excluded code may both be reported.
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Excludes2 — not included here — inherited from T80
The conditions below are not part of T80.6, but a patient may have both at the same time. When documentation supports it, T80.6 and the excluded code may both be reported.
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
What codes fall under T80.6? (3)
How long has T80.6 existed?
T80.6 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
What other codes are in the T80 family? (9)
- T80.0Air embolism following infusion, transfusion and therapeutic injectionnot billable
- T80.1Vascular complications following infusion, transfusion and therapeutic injectionnot billable
- T80.2Infections following infusion, transfusion and therapeutic injectionnot billable
- T80.3ABO incompatibility reaction due to transfusion of blood or blood productsnot billable
- T80.4Rh incompatibility reaction due to transfusion of blood or blood productsnot billable
- T80.ANon-ABO incompatibility reaction due to transfusion of blood or blood productsnot billable
- T80.5Anaphylactic reaction due to serumnot billable
- T80.8Other complications following infusion, transfusion and therapeutic injectionnot billable
- T80.9Unspecified complication following infusion, transfusion and therapeutic injectionnot billable