ICDcodes.org
FY2027

T50.915 — Adverse effect of multiple unspecified drugs, medicaments and biological substances

Not billable

Is T50.915 billable?

No — T50.915 is a non-billable header code. T50.915 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 3 billable codes beneath T50.915.

T50.915 at a glance

CodeT50.915
DescriptionAdverse effect of multiple unspecified drugs, medicaments and biological substances
BillableNo — header code
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Excludes1 — never code together — inherited from T36-T50

The conditions below can never be reported together with T50.915 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Code first — inherited from T36-T50

The underlying condition below must be sequenced before T50.915. T50.915 describes a manifestation and cannot be the principal or first-listed diagnosis.

  • , for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use additional code — inherited from Chapter 19

Report an additional code alongside T50.915 to fully describe the condition. T50.915 is sequenced first.

  • code to identify any retained foreign body, if applicable (Z18.-)

Use additional code — inherited from T36-T50

Report an additional code alongside T50.915 to fully describe the condition. T50.915 is sequenced first.

  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)

Excludes2 — not included here — inherited from Chapter 19

The conditions below are not part of T50.915, but a patient may have both at the same time. When documentation supports it, T50.915 and the excluded code may both be reported.

  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Excludes2 — not included here — inherited from T36-T50

The conditions below are not part of T50.915, but a patient may have both at the same time. When documentation supports it, T50.915 and the excluded code may both be reported.

  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)

Code also — inherited from T50.91

Two codes may be needed to describe the condition fully. Whether T50.915 is sequenced first depends on the reason for the encounter.

  • any specific drugs, medicaments and biological substances

What codes fall under T50.915? (3)

How long has T50.915 existed?

T50.915 first appears in FY2021 (FY2020 is not available, so it may have appeared then).

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the T50.91 family? (5)