ICDcodes.org
FY2027

R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious origin

Not billable

Is R65.1 billable?

No — R65.1 is a non-billable header code. R65.1 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 2 billable codes beneath R65.1.

R65.1 at a glance

CodeR65.1
DescriptionSystemic inflammatory response syndrome (SIRS) of non-infectious origin
BillableNo — header code
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Excludes1 — never code together

The conditions below can never be reported together with R65.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • sepsis- code to infection
  • severe sepsis (R65.2)

Code first

The underlying condition below must be sequenced before R65.1. R65.1 describes a manifestation and cannot be the principal or first-listed diagnosis.

  • underlying condition, such as:
  • heatstroke (T67.0-)
  • injury and trauma (S00-T88)

Excludes2 — not included here — inherited from Chapter 18

The conditions below are not part of R65.1, but a patient may have both at the same time. When documentation supports it, R65.1 and the excluded code may both be reported.

  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

What codes fall under R65.1? (2)

How long has R65.1 existed?

R65.1 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the R65 family? (1)