F19.221 — Other psychoactive substance dependence with intoxication delirium
Is F19.221 billable?
Yes — F19.221 is billable for FY2027. F19.221 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. F19.221 may be submitted for encounters from October 1, 2026 through September 30, 2027.
F19.221 at a glance
| Code | F19.221 |
|---|---|
| Description | Other psychoactive substance dependence with intoxication delirium |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does F19.221 group to?
F19.221 sits in MDC 20 and helps define the logic of 4 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 894Alcohol, Drug Abuse or Dependence, Left AMAmedical
- 895Alcohol, Drug Abuse or Dependence with Rehabilitation Therapymedical
- 896Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCCmedical
- 897Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCCmedical
As a secondary diagnosis, F19.221 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is F19.221 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to F19.221. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Disorder › substance use › moderate or severe › substance intoxication delirium (of)
- Delirium, delirious › due to › psychoactive substance NEC intoxication › in › dependence (acute or subacute) (not alcohol- or drug-induced)
- Dependence › drug NEC › psychoactive NEC › with › intoxication › with › delirium (on) (syndrome)
Excludes1 — never code together — inherited from F19.2
The conditions below can never be reported together with F19.221 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from F19.22
The conditions below can never be reported together with F19.221 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- other psychoactive substance dependence with withdrawal (F19.23-)
Excludes2 — not included here — inherited from Chapter 5
The conditions below are not part of F19.221, but a patient may have both at the same time. When documentation supports it, F19.221 and the excluded code may both be reported.
- symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
How long has F19.221 existed?
F19.221 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.