ICDcodes.org
FY2027

E08.649 — Diabetes mellitus due to underlying condition with hypoglycemia without coma

Billable

Is E08.649 billable?

Yes — E08.649 is billable for FY2027. E08.649 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E08.649 may be submitted for encounters from October 1, 2026 through September 30, 2027.

E08.649 at a glance

CodeE08.649
DescriptionDiabetes mellitus due to underlying condition with hypoglycemia without coma
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

What Medicare edits apply to E08.649?

The Medicare Code Editor screens inpatient claims before they are grouped. These edits name E08.649 directly.

Manifestation code — never sequenced first — MCE edit 6

This code describes a manifestation of an underlying disease. The underlying condition must be sequenced before it, so it can never be the principal or first-listed diagnosis.

Which MS-DRGs does E08.649 group to?

E08.649 sits in MDC Pre and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 008Simultaneous Pancreas, Islet Cell and Kidney Transplantsurgical

How is E08.649 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E08.649. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Diabetes, diabetic › due to underlying condition › with › hypoglycemia (mellitus) (sugar)

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E08.649 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E08

The conditions below can never be reported together with E08.649 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
  • type 2 diabetes mellitus (E11.-)

Code first — inherited from E08

The underlying condition below must be sequenced before E08.649. E08.649 describes a manifestation and cannot be the principal or first-listed diagnosis.

  • the underlying condition, such as:
  • congenital rubella (P35.0)
  • Cushing's syndrome (E24.-)
  • cystic fibrosis (E84.-)
  • malignant neoplasm (C00-C96)
  • malnutrition (E40-E46)
  • pancreatitis and other diseases of the pancreas (K85-K86.-)

Use additional code — inherited from E08

Report an additional code alongside E08.649 to fully describe the condition. E08.649 is sequenced first.

  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)

Use additional code — inherited from E08.64

Report an additional code alongside E08.649 to fully describe the condition. E08.649 is sequenced first.

  • code for hypoglycemia level, if applicable (E16.A-)

How long has E08.649 existed?

E08.649 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the E08.64 family? (1)